There has been a crash between a coach and motorcyclist on the A435.
Police were called to the main road near Rendcomb just after 4pm.
Paramedics are helping the motorcyclist and road closures are being put in place.
The A435 is now closed at Severn Springs and at the main road junction for Cirencester.
Roads from Upper Cobberly and Cowely are also affected.
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